Intestinal infections caused by protozoa and helminths are considered a major cause of diseases by infectious processes in the world.The present study aims to conduct a survey regarding the recent years of the prevalence of intestinal parasites in school children in various cities in Brazil, identifying which species are most commonly found and the
Environmental and biotic correlates to lionfish invasion success in Bahamian coral reefs.
Lionfish (Pterois volitans), venomous predators from the Indo-Pacific, are recent invaders of the Caribbean Basin and southeastern coast of North America.Quantification of invasive lionfish abundances, along with potentially important physical and biological environmental characteristics, permitted inferences about the invasion process of reefs on
Multi drug resistance in Colorectal Cancer- approaches to overcome, advancements and future success
A significant obstacle to treating cancer is multidrug resistance (MDR), which is the capacity of cancerous cells to develop resistance to both traditional and cutting-edge chemotherapeutic treatments.Following the initial discovery that cellular pumps reliant on ATP were the root of chemotherapy resistance, more research has revealed the involveme
The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.
DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous mutations in this domain, including C
Accurate genome relative abundance estimation based on shotgun metagenomic reads.
Accurate estimation of microbial community composition based on metagenomic sequencing data is fundamental for subsequent metagenomics analysis.Prevalent estimation methods are mainly based on directly summarizing alignment results or its variants; often result in biased and/or unstable estimates.We have developed a unified probabilistic framework